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Evaluation of prognostic value of cell adhesion molecules in chronic hepatitis C therapy J. Venom. Anim. Toxins incl. Trop. Dis.
Abdallah,N; Morsi,M; Hamed,N; Abdel Aziz,H.
The most reliable determination of severity and prognosis in chronic viral hepatitis is the histological staging of the disease, which comprises an invasive procedure and is often not well accepted by patients. The search for alternative non-invasive methods is mandatory especially in follow-ups after initial assessment by biopsy. The aim of this study was to evaluate the role of vascular cell adhesion molecule-1 (VCAM-1) and intercellular adhesion molecule-1 (ICAM-1) in patients under interferon alpha therapy whether responsive or non-responsive to therapy. Thirty chronic hepatitis C patients (CHC) under combined therapy of interferon-α with ribavirin, whether responsive or non-responsive, were included in the study as well as ten healthy controls. Serum...
Tipo: Info:eu-repo/semantics/article Palavras-chave: ICAM-1; VCAM-1; Interferon; Ribavirin; Chronic hepatitis C.
Ano: 2010 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1678-91992010000300010
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